Emergency Medicine Research

Research within the Department of Emergency Medicine is a core mission of our Department. The research mission overlaps and supports the other department missions of patient care, education and faculty development. The research mission engages faculty, fellows, residents, students and research staff.

Laboratory Research Group

 
Mark Angelos, MD
Investigator
Andy Chen, PhD
Investigator
Mahmood Khan, PhD
Investigator
 
Alan Blumberg
Research Associate
Ariel Basye
Research Assistant
 
The department has a long standing laboratory research effort initially lead by Dr. Charles Brown from 1985-1995 and subsequently led by Dr. Angelos. Since 1995, we have trained 1 post-doc and 9 research fellows and graduate students, three of whom obtained their PhD and 3 of whom obtained their Master’s Degree. In 2012, we successfully recruited Dr. Andy Chen, a NIH funded investigator and in 2013 we recruited a new research scientist, Dr. Mahmoud Khan who comes with partial NIH support. We currently have 2 large, well-resourced laboratories located in the Davis Heart Lung Research Institute. Our laboratory research program focuses on cardiac injury, specifically redox regulation of CV disease, ischemia reperfusion injury, oxygen therapy and cardiac regenerative cell therapy. Contact Individual: Dr. Angelos
 

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Clinical Research Group

 
Jeffrey Caterino, MD
Investigator
Thomas Terndrup, MD
Investigator
Howard Werman, MD
Investigator
 
Michael Hill, RN
Research Specialist
Heidi Gehring
Research Coordinator
Melanie Heinlein
Research Assistant
Julie Caldwell
Research Assistant
 
Subrahmanyam Darbha
Statistician
 
In recent years we have built up a strong clinical research program led by Dr. Jeffrey Caterino. In 2012-13, we expanded our clinical research staff from 1 to 5 individuals. This staff provides project management, subject enrollment, IRB assistance, and statistical support to clinical investigators and ongoing clinical studies in the Department. Through our collaboration with Neurology, we now can provide around-the-clock enrollment of subjects for clinical trials.
 

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Current Clinical Research Topics

 
Neurological Emergencies, NETT: Led by Dr. Michel Torbey in the Department of Neurology, Ohio State is a site for the NIH-funded Neurological Emergencies Treatment Trial (NETT) Network. Emergency Medicine collaborates closely in all NETT-sponsored studies, for example trials of intensive glucose control in stroke patients (Stroke Hyperglycemia Insulin Network Effect - SHINE) and Progesterone for the Treatment of Traumatic Brain Injury (ProTECT). Contact Individuals: Dr. Caterino and Dr. Angelos
 
Geriatrics: Research in older adults is a key focus of our Department. Led by Drs. Caterino and Laura Southerland, a variety of topics pertaining to older adults are being studied including infectious diseases, falls, functional status, and trauma. Supported by Dr. Caterino K23 award, we are currently enrolling patients for the NIH-funded project “Improving antimicrobial stewardship in older adults” whose goal is to improve accuracy of diagnosis and antibiotic selection in older ED patients. Contact Individual: Dr. Caterino
 
EMS: Dr Terndrup brings to Ohio State his NIH funded R18 research program looking at instrument validation for airway management by paramedics. Contact Individual: Dr. Terndrup
 
Behavioral Emergencies: The Department is one of eight sites for the NIH-funded Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE) trial. ED-SAFE is a multiphase study aimed at improving identification and care of patients with self-harm who present to the ED. Contact Individual: Dr. Caterino
 
Trauma and EMS research: ED investigators have successfully obtained funding through several external agencies to study outcomes in both the Ohio Trauma Registry and Central Ohio Trauma Registry including effectiveness of aeromedical transport in certain populations and effect of geriatric-specific triage guidelines. Contact Individual: Dr. Werman
 
Industry:The Department also participates in a number of industry-sponsored trials of new laboratory tests and therapeutics at any given time. Contact Individual: Dr. Caterino
 

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Education Research

 
David Bahner, MD
Investigator
Diane Gorgas, MD
Investigator
Sorabh Khandelwal, MD
Investigator
Nicholas Kman, MD
Investigator
 
Daniel Martin, MD
Investigator
 
In addition to our laboratory and clinical research programs, we have a core group of faculty educators in our department who are engaged in educational research. Dr. Sorabh Khandelwal and Dr. Nick Kman are focused on Education of Medical students and Dr. Dan Martin and Dr. Diane Gorgas with the residency leadership team our examining teaching methods in residency learning. Dr. David Bahner leads a nationally recognized program surrounding ultrasound education. These educational research areas represent important avenues of research for our specialty. If interested in educational research involvement, please contact the lead individuals for each area.
 

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Clinical Research Projects

 
Finally, there are always opportunities for faculty, residents, and students to engage in non-funded clinical research projects to address interesting clinical questions which frequently arise in the practice of emergency medicine. These projects frequently serve to help residents meet their graduation scholarly project requirement. For assistance in these projects please contact Dr. Caterino to coordinate support efforts.
 

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Future

 
The future of research in the Department of Emergency Medicine is bright. We are strongly committed to growing this mission over the next years in conjunction with the College of Medicine’s goal to increase our research standing. Both our laboratory and clinical research programs currently receive NIH funding, which we anticipate will continue to grow. As our research mission grows, we are anxious to recruit additional research core faculty and provide research training opportunities to our students, residents and fellows.
 

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Collaboration

 
The Department of Emergency Medicine has a long history of both intra- and inter-institutional collaboration. With over 120,000 patient visits per year between our two clinical sites, we have a large and diverse patient population. We are constantly seeking opportunities to expand our research mission and actively seek out additional potential collaborators both within and outside of our institution. Clinical research studies conducted within the emergency department at Ohio State are expected to have Emergency Medicine faculty input and involvement. We encourage potential collaborators to contact us early in their study design to ensure effective collaboration.
 
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